Used in class two years ago. There is one fold in the middle of the page. I don't think there are any markings, but I can't say for sure because there are many pages. Also, it's been stored at home, so please only consider if you're okay with that. There is no pet odor or tobacco odor. "Smith Organic Chemistry, Volume 1" Koichiro Oshima / Takashi Yamamoto / Janice Gorzynski Smith Price: ¥6500 #KoichiroOshima #Koichiro_Oshima #TakashiYamamoto #Takashi_Yamamoto #JaniceGorzynskiSmith #Janice_Gorzynski_Smith #book #nature/chemistry