There are no scratches or stains, but there are some areas with writing. There are sections highlighted with fluorescent markers and notes on the meanings of English words that appeared in longer passages. There is writing on the answer pages, but there is no writing that would interfere with solving the problems! Please refrain from purchasing if you are concerned about the writing. The photos show the pages with the most writing. Note that the permanent markings, such as fluorescent markers, are only present in the 2022 edition. Immediate purchase is welcome! "Hoshi University of Pharmacy" Kyogakusha #Kyogakusha #Book