HARIUL Wrinkle Improvement Cream Medicated Cream NA 15g x 2 [Cream to Improve Wrinkles] The active ingredient niacinamide improves wrinkles around the eyes and mouth. It also contains moisturizing support ingredients for firm, hydrated skin. [Also for Spot Treatment*] Niacinamide prevents the accumulation of UV damage received during the day, leading to transparent skin.