Otsuka Pharmaceutical InnerSignal Rejuvenate One a Quasi-drug, Medicated All-in-One Unique medicated active ingredient, Energy Signal Works on the mother cells at the base of the skin, enhancing energy metabolism. By promoting turnover, it expels melanin along with old cells, leading to clear, transparent skin. With its unique time-release penetration technology, it achieves the moisturizing effect of using a full skincare line. Purchase date: 2025.10 Single-use type, so it's hygienic! With booklet Thank you for viewing. Please read the product description to the end. Caution Image, unauthorized use prohibited × To prevent substitution, cancellations and returns are not accepted. Please understand. We will ship anonymously. If you are nervous or seeking perfection, please refrain from purchasing. Thank you. Please check the images carefully. Although it is new and unopened, please understand that it has been in someone's possession once before purchasing. As I am not a specialist, I cannot answer questions about usage or efficacy. New, unused, unopened product Price reduction not accepted Not for individual sale